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Sergio Lopeza Beatriz Bermudez Sergio de la Paz Sara Jaramillo Rocio Abia Francisco Murianafat intake human Mediterranean diet nonhuman Humans Review Protection animal Animals drug mechanism diet Mediterranean dietary intake ischemic heart disease risk reduction Risk Reduction Behavior cardiovascular disease evidence based medicine Evidence-Based Medicine healthy diet hypertension lipid composition obesity oleic acid polyphenol Protective Factors randomized controlled trial (topic) risk assessment Risk Assessment risk factor Risk Factors apoptosis aspartyl aminopeptidase Blood Preservation Blood pressure blood storage cardiac muscle cell cholesterol transport Dahl salt sensitive rat diastolic blood pressure disease severity drug efficacy essential hypertension food frequency questionnaire glutamyl aminopeptidase Healthy Diet hypercholesterolemia Hypertension Minor constituents nitric oxide Oleic acid Olive oil Olive oil pathophysiology Polyphenols sunflower oil systolic blood pressure triolein virgin olive oil Virgin olive oil