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Weihua Wang ZhanJiang Han Dongqi Guo Yanju Xiangarticle Ethyl carbamate Mechanism research Musalais Toxicity prediction Transcriptomics sequencing Wnt protein Wnt signaling alcohol dehydrogenase animal experiment animal model animal tissue carcinogenesis concentration (parameter) controlled study cyclin D1 cytochrome P450 fermented beverage gene identification glutathione transferase A1 glutathione transferase A2 glutathione transferase A5 glutathione transferase P1 liver toxicity nephrotoxicity nonhuman p53 signaling protein analysis protein metabolism protein p53 rat regulatory mechanism sequence analysis toxicity testing transcriptomics upregulation urethan