TY - JOUR KW - Animals KW - Blood Preservation KW - Blood pressure KW - Dahl salt sensitive rat KW - diet KW - Mediterranean KW - Evidence-Based Medicine KW - Healthy Diet KW - Humans KW - Hypertension KW - Mediterranean diet KW - Minor constituents KW - Oleic acid KW - Olive oil KW - Polyphenols KW - Protective Factors KW - Review KW - Risk Assessment KW - Risk Factors KW - Risk Reduction Behavior KW - Virgin olive oil KW - animal KW - apoptosis KW - aspartyl aminopeptidase KW - blood storage KW - cardiac muscle cell KW - cardiovascular disease KW - cholesterol transport KW - diastolic blood pressure KW - dietary intake KW - disease severity KW - drug efficacy KW - drug mechanism KW - essential hypertension KW - evidence based medicine KW - fat intake KW - food frequency questionnaire KW - glutamyl aminopeptidase KW - Healthy Diet KW - human KW - hypercholesterolemia KW - Hypertension KW - ischemic heart disease KW - lipid composition KW - nitric oxide KW - nonhuman KW - obesity KW - Oleic acid KW - Olive oil KW - pathophysiology KW - polyphenol KW - Protection KW - randomized controlled trial (topic) KW - Risk Assessment KW - risk factor KW - risk reduction KW - sunflower oil KW - systolic blood pressure KW - triolein KW - Virgin olive oil AU - Sergio Lopeza AU - Beatriz Bermudez AU - Sergio Montserrat-de la Paz AU - Sara Jaramillo AU - Rocio Abia AU - Francisco Muriana AB - The incidence of high blood pressure (BP) along with other cardiovascular (CV) risk factors on human health has been studied for many years. These studies have proven a link between unhealthy dietary habits and sedentary lifestyle with the onset of hypertension, which is a hallmark of CV and cerebrovascular diseases. The Mediterranean diet, declared by the UNESCO as an Intangible Cultural Heritage since 2013, is rich in vegetables, legumes, fruits and virgin olive oil. Thanks to its many beneficial effects, including those with regard to lowering BP, the Mediterranean diet may help people from modern countries to achieve a lower occurrence of CV disease. Data from human and animal studies have shown that the consumption of virgin olive oil shares most of the beneficial effects of the Mediterranean diet. Virgin olive oil is the only edible fat that can be consumed as a natural fruit product with no additives or preservatives, and contains a unique constellation of bioactive entities, namely oleic acid and minor constituents. In this review, we summarize what is known about the effects of virgin olive oil on hypertension. DO - 10.2174/1570161114666160118105137 M1 - 4 N1 - Publisher: Bentham Science Publishers B.V. N2 - The incidence of high blood pressure (BP) along with other cardiovascular (CV) risk factors on human health has been studied for many years. These studies have proven a link between unhealthy dietary habits and sedentary lifestyle with the onset of hypertension, which is a hallmark of CV and cerebrovascular diseases. The Mediterranean diet, declared by the UNESCO as an Intangible Cultural Heritage since 2013, is rich in vegetables, legumes, fruits and virgin olive oil. Thanks to its many beneficial effects, including those with regard to lowering BP, the Mediterranean diet may help people from modern countries to achieve a lower occurrence of CV disease. Data from human and animal studies have shown that the consumption of virgin olive oil shares most of the beneficial effects of the Mediterranean diet. Virgin olive oil is the only edible fat that can be consumed as a natural fruit product with no additives or preservatives, and contains a unique constellation of bioactive entities, namely oleic acid and minor constituents. In this review, we summarize what is known about the effects of virgin olive oil on hypertension. SP - 323 EP - 329 TI - Virgin Olive Oil and Hypertension UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84978204626&doi=10.2174%2f1570161114666160118105137&partnerID=40&md5=080b48240a81d10b3c14302d88c6d06c VL - 14 SN - 15701611 (ISSN) ER -