TY - JOUR
KW - AIMs
KW - African
KW - Afrodescendant population
KW - American Indian
KW - article
KW - Colombia
KW - DNA
KW - European
KW - Hispanic
KW - ancestry group
KW - gene frequency
KW - gene structure
KW - genetic database
KW - human
KW - indel mutation
KW - population genetics
KW - priority journal
AU - B. Martinez
AU - R. Pereira
AU - K. Meza
AU - L. Hernandez
AU - A. Amorim
AU - J. Marrugo
AU - L. Gusmao
AB - San Basilio de Palenque is located in Colombia, and was founded by escaped slaves mainly from Cartagena in the sixteenth century. For its history, traditions, ethnicities, culture and language, San Basilio de Palenque has been declared as Intangible Cultural Heritage of Humanity by UNESCO. Insertion/deletion polymorphisms (InDels) have considerable potential in the field of identification and ancestry assessment, since they combine desirable characteristics as genetic markers as simplicity of analysis through PCR and capillary electrophoresis. In the present work a sample from San Basilio de Palenque population (n = 187) was characterized using 46 autosomalAIM-indels. A database was built for genotypic and allelic frequencies, and used to assess the genetic ancestry of this peculiar group. As expected for an Afrodescendant population, the most representative ancestry estimate was African with 81.2\%, followed by 10.6\% European, and 8.2\% Native American contributions. The results obtained were compared with previous estimates for a sub region of the Department of Bolivar, called Montes de Maria, which also include San Basilio de Palenque. In the pre-Hispanic era, this region was populated by Zenú indigenous, who mixed with the Spanish settlers. The African ancestry in San Basilio is four times higher than in Bolivar. Interestingly, the second component in San Basilio is European while in Bolivar it is Native American. Our findings can be useful to investigate the genetic structure of Bolivar department and show the importance of considering the heterogeneity that exists when selecting reference populations for forensic applications.
BT - Forensic Science International: Genetics Supplement Series
DA - dec
DO - 10.1016/j.fsigss.2017.09.105
LA - English
N1 - Publisher: Elsevier B.V.
N2 - San Basilio de Palenque is located in Colombia, and was founded by escaped slaves mainly from Cartagena in the sixteenth century. For its history, traditions, ethnicities, culture and language, San Basilio de Palenque has been declared as Intangible Cultural Heritage of Humanity by UNESCO. Insertion/deletion polymorphisms (InDels) have considerable potential in the field of identification and ancestry assessment, since they combine desirable characteristics as genetic markers as simplicity of analysis through PCR and capillary electrophoresis. In the present work a sample from San Basilio de Palenque population (n = 187) was characterized using 46 autosomalAIM-indels. A database was built for genotypic and allelic frequencies, and used to assess the genetic ancestry of this peculiar group. As expected for an Afrodescendant population, the most representative ancestry estimate was African with 81.2\%, followed by 10.6\% European, and 8.2\% Native American contributions. The results obtained were compared with previous estimates for a sub region of the Department of Bolivar, called Montes de Maria, which also include San Basilio de Palenque. In the pre-Hispanic era, this region was populated by Zenú indigenous, who mixed with the Spanish settlers. The African ancestry in San Basilio is four times higher than in Bolivar. Interestingly, the second component in San Basilio is European while in Bolivar it is Native American. Our findings can be useful to investigate the genetic structure of Bolivar department and show the importance of considering the heterogeneity that exists when selecting reference populations for forensic applications.
PY - 2017
SP - 224
EP - 225
T2 - Forensic Science International: Genetics Supplement Series
TI - Ancestry estimates in afrodescendant population from San Basilio de Palenque, Colombia
UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029689419&doi=10.1016%2fj.fsigss.2017.09.105&partnerID=40&md5=e5de6f6cec2d76435b10cb3760cc893f
VL - 6
SN - 18751768 (ISSN)
ER -