TY - JOUR KW - fat intake KW - human KW - Mediterranean diet KW - nonhuman KW - Humans KW - Review KW - Protection KW - animal KW - Animals KW - drug mechanism KW - diet KW - Mediterranean KW - dietary intake KW - ischemic heart disease KW - risk reduction KW - Risk Reduction Behavior KW - cardiovascular disease KW - evidence based medicine KW - Evidence-Based Medicine KW - healthy diet KW - hypertension KW - lipid composition KW - obesity KW - oleic acid KW - polyphenol KW - Protective Factors KW - randomized controlled trial (topic) KW - risk assessment KW - Risk Assessment KW - risk factor KW - Risk Factors KW - apoptosis KW - aspartyl aminopeptidase KW - Blood Preservation KW - Blood pressure KW - blood storage KW - cardiac muscle cell KW - cholesterol transport KW - Dahl salt sensitive rat KW - diastolic blood pressure KW - disease severity KW - drug efficacy KW - essential hypertension KW - food frequency questionnaire KW - glutamyl aminopeptidase KW - Healthy Diet KW - hypercholesterolemia KW - Hypertension KW - Minor constituents KW - nitric oxide KW - Oleic acid KW - Olive oil KW - Olive oil KW - pathophysiology KW - Polyphenols KW - sunflower oil KW - systolic blood pressure KW - triolein KW - virgin olive oil KW - Virgin olive oil AU - Sergio Lopeza AU - Beatriz Bermudez AU - Sergio de la Paz AU - Sara Jaramillo AU - Rocio Abia AU - Francisco Muriana AB - The incidence of high blood pressure (BP) along with other cardiovascular (CV) risk factors on human health has been studied for many years. These studies have proven a link between unhealthy dietary habits and sedentary lifestyle with the onset of hypertension, which is a hallmark of CV and cerebrovascular diseases. The Mediterranean diet, declared by the UNESCO as an Intangible Cultural Heritage since 2013, is rich in vegetables, legumes, fruits and virgin olive oil. Thanks to its many beneficial effects, including those with regard to lowering BP, the Mediterranean diet may help people from modern countries to achieve a lower occurrence of CV disease. Data from human and animal studies have shown that the consumption of virgin olive oil shares most of the beneficial effects of the Mediterranean diet. Virgin olive oil is the only edible fat that can be consumed as a natural fruit product with no additives or preservatives, and contains a unique constellation of bioactive entities, namely oleic acid and minor constituents. In this review, we summarize what is known about the effects of virgin olive oil on hypertension. BT - Current Vascular Pharmacology DO - 10.2174/1570161114666160118105137 LA - English M1 - 4 N1 - Publisher: Bentham Science Publishers B.V. N2 - The incidence of high blood pressure (BP) along with other cardiovascular (CV) risk factors on human health has been studied for many years. These studies have proven a link between unhealthy dietary habits and sedentary lifestyle with the onset of hypertension, which is a hallmark of CV and cerebrovascular diseases. The Mediterranean diet, declared by the UNESCO as an Intangible Cultural Heritage since 2013, is rich in vegetables, legumes, fruits and virgin olive oil. Thanks to its many beneficial effects, including those with regard to lowering BP, the Mediterranean diet may help people from modern countries to achieve a lower occurrence of CV disease. Data from human and animal studies have shown that the consumption of virgin olive oil shares most of the beneficial effects of the Mediterranean diet. Virgin olive oil is the only edible fat that can be consumed as a natural fruit product with no additives or preservatives, and contains a unique constellation of bioactive entities, namely oleic acid and minor constituents. In this review, we summarize what is known about the effects of virgin olive oil on hypertension. PY - 2016 SP - 323 EP - 329 T2 - Current Vascular Pharmacology TI - Virgin Olive Oil and Hypertension UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84978204626&doi=10.2174%2f1570161114666160118105137&partnerID=40&md5=080b48240a81d10b3c14302d88c6d06c VL - 14 SN - 15701611 (ISSN) ER -